
Hillary Clinton is expected to tell American voters they must come together to face the country's challenges, as she makes history by accepting the Democratic presidential nomination.
The first woman nominated by a major party will tell the Democratic convention in Philadelphia the country faces a "moment of reckoning".
Mrs Clinton will face Republican Donald Trump in November's election.
She will be introduced on stage by daughter Chelsea Clinton.
"Every generation of Americans has come together to make our country freer, fairer, and stronger," she will say, according to prepared remarks sent to the media in advance.
"None of us can do it alone. That's why we are stronger together."
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Her high-stakes remarks on the closing night of the four-day convention follow a rousing speech by US President Barack Obama.
He said on Wednesday there had never been a man or woman more qualified than Mrs Clinton to serve as president.
The 36-year-old daughter of Mrs Clinton and former US president Bill Clinton, Chelsea, will explain why her other parent is destined to return to the White House.


Mrs Clinton, 68, is tasked with both laying out her plans to seal Mr Obama's legacy while also convincing voters to support her after facing low approval ratings.
The former secretary of state's character has been tarnished by a controversy surrounding her use of private email while at the State Department as well as a tough primary fight with Senator Bernie Sanders, which left some voters embittered by his loss.
In his speech at the Wells Fargo Center, Mr Obama described Mrs Clinton as a persistent leader who has "been there for us, even if we haven't always noticed".
He also struck an optimistic tone about the future of America, a message that Mrs Clinton is expected to continue in her remarks on Thursday.
Other speakers scheduled for the final night include House Democratic leader Nancy Pelosi, New York Governor Andrew Cuomo and US Senator Sherrod Brown, who was once considered to be Mrs Clinton's running mate.
Singers Katy Perry and Carole King are also scheduled to perform at the event.
The Democratic convention has been marked by a star-studded week of powerful speeches from President Obama, First Lady Michelle Obama, Vice-President Joe Biden, Vermont Senator Bernie Sanders as well as former president Bill Clinton.
While most convention speakers focused on a bright future under a Clinton presidency, many carried the theme of attacking Republican presidential candidate Donald Trump and his portrayal of America.
Mr Obama suggested Mr Trump was a "home-grown demagogue" while Mrs Obama skewered the businessman for his "hateful language".
Mrs Clinton and Mr Trump are set for an election battle widely considered to be a tight race when voters head to the polls in November.
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